Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gad2  glutamic acid decarboxylase 2   (Synonyms: 6330404F12Rik, Gad-2, GAD65, GAD(65))
Results	Reference
1	J:103009 Acosta ML, Kalloniatis M, Christie DL, Creatine transporter localization in developing and adult retina: importance of creatine to retinal function. Am J Physiol Cell Physiol. 2005 Oct;289(4):C1015-23
1*	J:207154 Balasubramanian R, Bui A, Ding Q, Gan L, Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina. Gene Expr Patterns. 2014 Jan;14(1):1-8
1	J:132519 Bumsted-O'Brien KM, Hendrickson A, Haverkamp S, Ashery-Padan R, Schulte D, Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina. J Comp Neurol. 2007 Nov 1;505(1):58-72
1	J:161400 Carney RS, Mangin JM, Hayes L, Mansfield K, Sousa VH, Fishell G, Machold RP, Ahn S, Gallo V, Corbin JG, Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala. Neural Dev. 2010;5:14
1	J:99180 Corbetta S, Gualdoni S, Albertinazzi C, Paris S, Croci L, Consalez GG, de Curtis I, Generation and characterization of rac3 knockout mice. Mol Cell Biol. 2005 Jul;25(13):5763-76
1	J:83565 De Melo J, Qiu X, Du G, Cristante L, Eisenstat DD, Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina. J Comp Neurol. 2003 Jun 23;461(2):187-204
1	J:206591 Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A, Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Development. 2014 Jan;141(2):377-88
1	J:271140 Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W, Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.e4
1	J:147448 Ding Q, Chen H, Xie X, Libby RT, Tian N, Gan L, BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J Neurosci. 2009 Apr 1;29(13):3992-4003
1	J:335507 Ding Z, Huang G, Wang T, Duan W, Li H, Wang Y, Jia H, Yang Z, Wang K, Chu X, Kurtz-Nelson EC, Ahlers K, Earl RK, Han Y, Feliciano P, Chung WK, Eichler EE, Jiang M, Xiong B, Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice. Biol Psychiatry. 2023 Mar 15;
1	J:119663 Feng L, Xie X, Joshi PS, Yang Z, Shibasaki K, Chow RL, Gan L, Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina. Development. 2006 Dec;133(24):4815-25
1	J:168595 Feng L, Xie ZH, Ding Q, Xie X, Libby RT, Gan L, MATH5 controls the acquisition of multiple retinal cell fates. Mol Brain. 2010;3:36
1	J:186614 Franco SJ, Gil-Sanz C, Martinez-Garay I, Espinosa A, Harkins-Perry SR, Ramos C, Muller U, Fate-restricted neural progenitors in the mammalian cerebral cortex. Science. 2012 Aug 10;337(6095):746-9
1	J:174747 Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Muller U, Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron. 2011 Feb 10;69(3):482-97
1*	J:339296 Fries M, Brown TW, Jolicoeur C, Boulan B, Boudreau-Pinsonneault C, Javed A, Abram P, Cayouette M, Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985
1	J:253958 Fujimura N, Kuzelova A, Ebert A, Strnad H, Lachova J, Machon O, Busslinger M, Kozmik Z, Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation. Dev Biol. 2018 Jan 1;433(1):47-60
1	J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861
1	J:257913 Goodson NB, Nahreini J, Randazzo G, Uruena A, Johnson JE, Brzezinski JA 4th, Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Dev Biol. 2018 Feb 1;434(1):149-163
1	J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94
1	J:212111 Hua ZL, Jeon S, Caterina MJ, Nathans J, Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E3005-14
1	J:237687 Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L, Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. 2016 Oct 19;92(2):392-406
1	J:153525 Hurtado-Chong A, Yusta-Boyo MJ, Vergano-Vera E, Bulfone A, de Pablo F, Vicario-Abejon C, IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Eur J Neurosci. 2009 Sep;30(5):742-55
1	J:325069 Ichise M, Sakoori K, Katayama KI, Morimura N, Yamada K, Ozawa H, Matsunaga H, Hatayama M, Aruga J, Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics. Front Mol Neurosci. 2022;15:856315
1	J:210870 Ikeda K, Satake S, Onaka T, Sugimoto H, Takeda N, Imoto K, Kawakami K, Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice. J Physiol. 2013 Jul 1;591(Pt 13):3433-49
1	J:151918 Jiang H, Xiang M, Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. J Neurosci. 2009 Aug 19;29(33):10449-59
1	J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16
1	J:302827 Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M, Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015 May 13;8:28
1	J:256001 Jung EM, Moffat JJ, Liu J, Dravid SM, Gurumurthy CB, Kim WY, Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707
1	J:176166 Kay JN, Voinescu PE, Chu MW, Sanes JR, Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate. Nat Neurosci. 2011 Aug;14(8):965-72
1	J:136568 Kiehl TR, Fischer SE, Ezzat S, Asa SL, Mice lacking the transcription factor Ikaros display behavioral alterations of an anti-depressive phenotype. Exp Neurol. 2008 May;211(1):107-14
1*	J:193557 Kosaka Y, Kin H, Tatetsu M, Uema I, Takayama C, Distinct development of GABA system in the ventral and dorsal horns in the embryonic mouse spinal cord. Brain Res. 2012 Nov 27;1486:39-52
1*	J:127151 Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdelyi F, Baranyi M, Katarova ZD, Szabo G, GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5. Dev Dyn. 2007 Dec;236(12):3532-44
1	J:304308 Kweon H, Jung WB, Im GH, Ryoo J, Lee JH, Do H, Choi Y, Song YH, Jung H, Park H, Qiu LR, Ellegood J, Shim HJ, Yang E, Kim H, Lerch JP, Lee SH, Chung WS, Kim D, Kim SG, Kim E, Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors. Cell Rep. 2021 Feb 23;34(8):108780
1	J:257839 Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabo G, Jain RK, Kohling R, Vasudevan A, Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Res. 2018 Feb;28(2):221-248
1	J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544
1	J:317376 Lin CW, Liu HY, Chen CY, Hsueh YP, Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains. Innate Immun. 2014 Feb;20(2):161-72
1	J:143446 Liu C, Nathans J, An essential role for frizzled 5 in mammalian ocular development. Development. 2008 Nov;135(21):3567-76
1	J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027
1	J:177911 Lu PP, Ramanan N, Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination. J Neurosci. 2011 Nov 16;31(46):16651-64
1	J:193051 Marks C, Belluscio L, Ibanez CF, Critical role of GFRalpha1 in the development and function of the main olfactory system. J Neurosci. 2012 Nov 28;32(48):17306-20
1*	J:160811 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE, Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. J Neurosci. 2010 Jun 2;30(22):7453-65
1	J:305858 Morarach K, Mikhailova A, Knoflach V, Memic F, Kumar R, Li W, Ernfors P, Marklund U, Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing. Nat Neurosci. 2021 Jan;24(1):34-46
1	J:86636 Nishida A, Furukawa A, Koike C, Tano Y, Aizawa S, Matsuo I, Furukawa T, Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat Neurosci. 2003 Dec;6(12):1255-63
1	J:230346 Omori Y, Kitamura T, Yoshida S, Kuwahara R, Chaya T, Irie S, Furukawa T, Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells. Genes Cells. 2015 May;20(5):408-26
1	J:263281 Ray TA, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert SW, Wright CV, Field GD, Kay JN, Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. Elife. 2018 Apr 3;7:e34241
1*	J:94923 Schurov IL, Handford EJ, Brandon NJ, Whiting PJ, Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Mol Psychiatry. 2004 Dec;9(12):1100-10
1*	J:115166 Shibasaki K, Takebayashi H, Ikenaka K, Feng L, Gan L, Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells. Gene Expr Patterns. 2007 Jan;7(1-2):57-65
1	J:279152 Shin W, Kweon H, Kang R, Kim D, Kim K, Kang M, Kim SY, Hwang SN, Kim JY, Yang E, Kim H, Kim E, Scn2a Haploinsufficiency in Mice Suppresses Hippocampal Neuronal Excitability, Excitatory Synaptic Drive, and Long-Term Potentiation, and Spatial Learning and Memory. Front Mol Neurosci. 2019;12:145
1	J:101317 Stewart L, Potok MA, Camper SA, Stifani S, Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina. J Neurochem. 2005 Sep;94(6):1739-45
1	J:243154 Sunagawa M, Shimizu-Okabe C, Kim J, Kobayashi S, Kosaka Y, Yanagawa Y, Matsushita M, Okabe A, Takayama C, Distinct development of the glycinergic terminals in the ventral and dorsal horns of the mouse cervical spinal cord. Neuroscience. 2017 Feb 20;343:459-471
1	J:235203 Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, Daftarian N, Biernaskie J, McFarlane S, Schuurmans C, Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgfbeta, and Erk Signaling. J Neurosci. 2016 Sep 7;36(36):9454-71
1	J:311881 Takeuchi A, Takahashi Y, Iida K, Hosokawa M, Irie K, Ito M, Brown JB, Ohno K, Nakashima K, Hagiwara M, Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage. Stem Cell Reports. 2020 Oct 13;15(4):883-897
1	J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442
1	J:95510 Treloar HB, Uboha U, Jeromin A, Greer CA, Expression of the neuronal calcium sensor protein NCS-1 in the developing mouse olfactory pathway. J Comp Neurol. 2005 Feb 7;482(2):201-16
1	J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441
1	J:328938 Vilchez-Acosta A, Manso Y, Cardenas A, Elias-Tersa A, Martinez-Losa M, Pascual M, Alvarez-Dolado M, Nairn AC, Borrell V, Soriano E, Specific contribution of Reelin expressed by Cajal-Retzius cells or GABAergic interneurons to cortical lamination. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2120079119
1	J:222242 Watanabe S, Sanuki R, Sugita Y, Imai W, Yamazaki R, Kozuka T, Ohsuga M, Furukawa T, Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. J Neurosci. 2015 May 20;35(20):8004-20
1	J:274446 Wei W, Liu B, Jiang H, Jin K, Xiang M, Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Mol Neurobiol. 2019 Mar;56(3):1719-1736
1	J:171660 Winpenny E, Lebel-Potter M, Fernandez ME, Brill MS, Gotz M, Guillemot F, Raineteau O, Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Dev. 2011;6:12
1	J:264478 Wu PR, Cho KKA, Vogt D, Sohal VS, Rubenstein JLR, The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex. Cereb Cortex. 2017 Sep 1;27(9):4303-4313
1	J:326953 Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G, Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex. Cell Rep. 2022 Jul 19;40(3):111085
1	J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271
1	J:212357 Xu JC, Xiao MF, Jakovcevski I, Sivukhina E, Hargus G, Cui YF, Irintchev A, Schachner M, Bernreuther C, The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice. J Cell Sci. 2014 Feb 1;127(Pt 3):641-52
1	J:255264 Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA, A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. Cell Rep. 2017 Oct 17;21(3):666-678
1	J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97